Principal Clinical Scientist

Principal Clinical Scientist (AI Training) About The Role What if your career-long expertise in clinical trial design and regulatory science could directly shape how AI understands and reasons about clinical evidence?

We're looking for a Principal Clinical Scientist to bring senior-level rigor to frontier AI research — ensuring the models influencing biomedical science are grounded in real-world regulatory standards.

This is a fully remote, flexible contract role built for experienced clinical scientists who want to contribute to something genuinely new. No AI background required — just deep command of clinical trial methodology and regulatory data interpretation.

Organization: AlignerrType: Hourly ContractLocation: RemoteCommitment: 10–40 hours/week What You'll Do Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI trainingInterpret and audit clinical trial results for accuracy, consistency, and regulatory relevanceEvaluate AI-generated clinical analyses for scientific soundness and alignment with regulatory expectations (FDA, EMA, or equivalent)Provide expert feedback that directly shapes how AI models reason about clinical trial data, outcomes, and methodologyHelp define standards for how cutting-edge AI systems engage with biomedical and clinical research evidence Who You Are Senior clinical scientist with hands-on experience designing protocols for regulatory submissionDeep expertise interpreting clinical data for regulatory agencies such as FDA, EMA, or equivalent bodiesStrong command of clinical research methodology, biostatistics, or translational scienceNaturally rigorous — you hold your work to the standard that real submissions demandDetail-oriented and able to clearly communicate complex scientific reasoning in writingComfortable working independently and asynchronously Nice to Have Prior experience with data annotation, data quality review, or evaluation systemsBackground in pharmacology, epidemiology, or health technology assessmentFamiliarity with AI tools or data-driven research platforms Why Join Us Work directly on frontier AI systems with real impact on clinical and biomedical researchInfluence how AI understands, evaluates, and communicates real-world clinical evidenceFully remote and flexible — work on your own schedule, from anywhereFreelance autonomy with the substance of meaningful, expert-level workCollaborate with world-leading AI research teams and labsPotential for ongoing work and contract extension as new projects launch